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A New Research Suggests At Least 75 Percent Of Human Genome Is Junk DNA

Human Genome
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A latest study has put forth some new calculations that indicate no more than 25 percent of the human genome is functional.

In work published online in Genome Biology and Evolution, Dan Graur reports the functional portion of the human genome probably falls between 10 percent and 15 percent, with an upper limit of 25 percent.

The rest is so-called junk DNA, or useless but harmless DNA.

The researchers from University of Houston in the US took a deceptively simple approach to determining how much of the genome is functional, using the deleterious mutation rate — that is, the rate at which harmful mutations occur — and the replacement fertility rate.

Both genome size and the rate of deleterious mutations in functional parts of the genome have previously been determined, and historical data documents human population levels.

Both genome size and the rate of deleterious mutations in functional parts of the genome have previously been determined, and historical data documents human population levels.

With that information, the researchers developed a model to calculate the decrease in reproductive success induced by harmful mutations, known as the “mutational load”, in relation to the portion of the genome that is functional.

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